ONE - RESEARCH
We conducted both in-vitro and in-vivo studies under the direction of Prof. Zvi Schwartz to
investigate whether in fact the implant would stimulate bone growth and osseointegration,
and accelerate healing times.
The outcome is an implant with a hydrophilic surface that enhances osseointegration as
never before.
The results of our research are astounding. Our new implant draws blood and promotes
protein selection as never before. The nanostructure we have perfected have the correct
surface energy and hydrophilic properties to simulate natural bone.

Published articles
Novel hydrophilic nanostructured microtexture on direct metal laser sintered Ti–6Al–4V surfaces enhances osteoblast response in vitro and osseointegration in a rabbit model
Journal of Biomedical Materials Research (JBMR), Part A, 2016
Sharon L. Hyzy, Alice Cheng, David J. Cohen, Gustavo Yatzkaier, Alexander J. Whitehead, Ryan M. Clohessy, Rolando A. Gittens, Barbara D. Boyan, Zvi Schwartz
Novel osteogenic Ti-6Al-4V device for restoration of dental function in patients with large bone deficiencies: design, development and implementation
Scientific Reports magazine, 08 February 2016
D.J. Cohen, A. Cheng, A. Kahn, M. A viram, A. J. Whitehead, S. L. Hyzy, R. M. Clohessy, B. D. Boyan & Z. Schwartz